NIHILISTIC INSPIRATION IN THE BLIND OWL OF SADEGH HEDAYAT MARZIEH BALIGHI


Stability Indicating HPLC-ECD Method for the Analysis of Clarithromycin in Pharmaceutical Dosage Forms: Method Scaling versus Re-Validation

Vitamin B-1 An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD).The method was validated using International Conference on Harmonization (ICH) guidelines wit

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SARS-CoV-2 SUD2 and Nsp5 Conspire to Boost Apoptosis of Respiratory Epithelial Cells via an Augmented Interaction with the G-Quadruplex of BclII

ABSTRACT The molecular mechanisms underlying how SUD2 recruits other proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to exert its G-quadruplex (G4)-dependent pathogenic function is unknown.Herein, Nsp5 was singled out as a binding partner of the Face Mist SUD2-N+M domains (SUD2core) with high affinity, through the surface l

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